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Associate Scientist, Process Development – Upstream

Forge Biologics

This is a Contract position in Las Vegas, NV posted May 10, 2022.

We are currently seeking an Associate Scientist, Process Development to join the Forge Biologics team.

This is an exciting entry-level opportunity to assist in the execution of laboratory experiments and protocols for upstream and downstream process development efforts.

The candidate will assist in process development protocols/studies to optimize procedures for unique viral vector platform process and to assist in the transfer of client programs.

The technician will work to meet production goals, notify management of any potential delays in the schedule, and make recommendations to resolve the issues.This position reports to the Associate Director of Upstream Process Development and is responsible for laboratory stocking, inventory management, and assisting in laboratory activities.

This includes preparing growth media, chemical buffers, solutions or other reagents that involve the mixing of subcomponents and preparing raw materials for use in production steps.

Work activities may also include performing laboratory techniques (cell culture, vector purification) in support of production of recombinant adeno-associated virus (rAAV) vectors.

It is expected that you will work as a member of the development team while accomplishing the timely completion of assignments and reporting of unexpected technical issues.ResponsibilitiesAssist with overall maintenance of the production and testing facilities.

This includes but may not be limited to performing quality systems checks, autoclaving of media, packing of biohazard material, monitoring or sanitizing equipment, preparing facility for production campaigns, and periodic cleaning of incubators, centrifuges, FPLCs, biological safety cabinets (BSCs), and other equipmentCulturing cells, performing transfections and/or infections with seed vectors, harvesting and lysing cells, and purifying vectors using density gradients, FPLC, or other techniquesProvide support in the receipt and distribution of incoming raw materials for research, preclinical, and clinical manufacturingUnpack reagents, maintaining proper cold storage, restock supplies in storerooms or laboratoriesQuarantine and prepare incoming raw materials intended for preclinical or clinical manufacturing for inspection and releaseAssist in maintaining proper inventories of raw materials and consumablesPrepares formulations and raw materials as specified in protocols without the introduction of contaminantsPrepare sterile reagents as dictated by procedures or management by filtration or steam autoclavingMaintains clean work environment in all work areasReports any discrepancies from protocols/study procedures or any materials preparation problems to managementDelivering results in a high paced environmentPackage and ship finished product to clients in accordance with procedures and regulationsAdditional responsibilities not listed may be assigned as needed by leadershipRequirementsBachelor’s degree in Biology, Chemistry, or relevant area; Associate’s degree with2 years of relevant experience may be consideredTechnical skill required for fundamental laboratory tasksWorking knowledge of cell culture techniques is preferredMust be self-motivating, organized and proactiveStrong technical aptitude including demonstrated experience in applying scientific reasoning to solve problemsStrong writing, verbal, and organizational skills are essentialAbility to work hours necessary to support production and/or product transfer activitiesAbility to work in loud noise environments and in Personal Protective Equipment (PPE) and cleanroom gowning attire as neededAbility to lift 50 lbsIn our commitment to safety of our employees and customers a COVID vaccination is required.